Picrasidine Q

CAS No. 101219-61-8

Picrasidine Q( —— )

Catalog No. M31232 CAS No. 101219-61-8

Picrasidine Q has the capacity of anti-cell transformation and anti-cancer, it might be a chemopreventive and chemotherapeutic agent by direct targeting FGFR2 and inhibiting cell proliferation of ESCC cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 380 In Stock
50MG Get Quote In Stock
100MG Get Quote In Stock

Biological Information

  • Product Name
    Picrasidine Q
  • Note
    Research use only, not for human use.
  • Brief Description
    Picrasidine Q has the capacity of anti-cell transformation and anti-cancer, it might be a chemopreventive and chemotherapeutic agent by direct targeting FGFR2 and inhibiting cell proliferation of ESCC cells.
  • Description
    Picrasidine Q has the capacity of anti-cell transformation and anti-cancer, it might be a chemopreventive and chemotherapeutic agent by direct targeting FGFR2 and inhibiting cell proliferation of ESCC cells.
  • In Vitro
    Picrasidine Q (0~60 μM; 3 hours; ESCC cells) suppresses downstream signaling of FGFR2 in ESCC cells.Picrasidine Q (0~60 μM; 48 and 72 hours; ESCC cells) induces cell cycle arrest and apoptosis.Picrasidine Q (0~60 μM; 24~72 hours; ESCC cells) suppresses the growth of ESCC cells.Picrasidine Q (0~60 μM; 30 minutes; JB6Cl41 cells) inhibits proliferation by inhibition of G1/S cell cycle transition.Picrasidine Q (12.5, 25 or 50 μM) can inhibit the FGFR2 kinase activity in a dose-dependent manner. Western Blot Analysis Cell Line:ESCC cells Concentration:0~60 μM Incubation Time:3 hours Result:Suppressed downstream signaling of FGFR2 in ESCC cells.Apoptosis Analysis Cell Line:ESCC cells Concentration:0~60 μM Incubation Time:48 and 72 hours Result:Induced cell cycle arrest and apoptosis.Cell Cytotoxicity Assay Cell Line:ESCC cells Concentration:0~60 μM Incubation Time:24~72 hours Result:Suppressed the growth of ESCC cells.Cell Cycle Analysis Cell Line:JB6Cl41 cells Concentration:0~60 μM Incubation Time:30 minutes Result:Inhibited proliferation by inhibition of G1/S cell cycle transition.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    101219-61-8
  • Formula Weight
    266.3
  • Molecular Formula
    C15H10N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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